课题组组长(PI),四川大学/康奈尔大学博士,加州大学圣地亚哥分校医学院博士后,四川省高层次人才项目获得者,第十二届华西青年榜样。主持国家自然科学基金等科研项目。与国内外多个顶尖机构建立了实质性合作。多次参加国际会议并作交流汇报。Nat Commun,Lancet Microbe等期刊审稿人。
美国微生物学会(ASM)会员,欧洲临床微生物与感染病学会(ESCMID)会员,国自然项目等评审专家;Microbiol Spectr等期刊编委或青年编委。
在病原微生物感染、宿主互作和防控领域开展了多年连续性研究,有成体系的发现。目前主要有4个研究方向:(1)临床重要病原菌的耐药和传播机制;(2)病原菌的致病机理和宿主体内互作机制;(3)肠道微生态对感染性疾病发生发展的调控作用;(4)利用噬菌体、小分子抑制剂等进行靶向干预和转化研究。在Cell Host Microbe, Lancet Microbe, Nat Commun, Nat Microbiol, Trends Microbiol, PLOS Med, ISME J, J Hepatol, Emerg Microbes Infect, Adv Sci, J Antimicrob Chemother, Antimicrob Agents Chemother等权威期刊上发表论文50余篇,ESI高被引3篇,总被引超过1600次,H指数22。
My current research focuses on four major areas: 1. Antimicrobial resistance and transmission mechanisms of clinically important pathogens; 2. Molecular mechanisms of microbial pathogenesis and host-pathogen interactions; 3. The regulatory role of the gut microbiota in the development and progression of infectious diseases; and 4. Translational research on targeted interventions using bacteriophages, small-molecule inhibitors, and other antimicrobial strategies.
I have published more than 50 peer-reviewed papers in leading international journals, including Cell Host Microbe, Lancet Microbe, Nat Commun, Nat Microbiol, Trends Microbiol, PLOS Med, ISME J, J Hepatol, Emerg Microbes Infect, Adv Sci, J Antimicrob Chemother, Antimicrob Agents Chemother, etc. My publications include three ESI Highly Cited Papers, with more than 1,600 citations and an H-index of 22. We welcome opportunities for communication and collaboration with researchers from diverse regions and backgrounds.
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